Rupp checks Boychuk/By S. Bradley

BOSTON — Two-goal deficits against Pittsburgh have been no problem for the Bruins to overcome this season.

However, for the first time in three meetings with the Penguins this season the Bruins failed to turn their comeback into a victory today.

Jordan Staal’s goal 3:25 into the third period turned out to be the game-winner after Boston had rallied from 2-0 down to tie the score in the second period of a 3-2 Pittsburgh win at TD Garden.

The Bruins, who had rallied from 4-2 and 2-0 down in their previous two meetings with the Penguins, had their overall winning streak ended at three.

Here’s a glance at the box score:

•Michael Ryder scored his second goal in as many games to tie the score with 8:19 left in the second period. He now has 13 goals on the season.

•Dennis Seidenberg scored the Bruins’ other goal and added an assist.

•Penguins super villain Matt Cooke recorded two assists, including the primary assist on Staal’s game-winner.

•The Bruins’ 46 shots on goal were both a season high for them and a season high for shots allowed by the Penguins. Seidenberg and Ryder led the way with seven shots on net apiece.